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Nasal Spray Treatment for Depression

Unlike traditional antidepressants, Spravato supports your brain’s natural pathways.

  • 1000+Successful Therapies
  • FlatironEasy to Access Location
  • Board-CertifiedPsychiatrist
Verified Patient Care

4.9

1,200+ Total Reviews

Highly Recommended

Across Google and Zocdoc, patients praise our care team for clear communication, thoughtful follow-up, and a calm, supportive environment.

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High Success Rate

A clinical study on patients with treatment-resistant depression found that combining an oral antidepressant with intranasal esketamine led to significant improvement. In the study, 70% of patients who received this combination showed improvement, compared to just over 50% who received a placebo

Want to learn more about Spravato treatment?

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Spravato (esketamine) nasal spray device

Spravato

As part of a treatment plan, your psychiatrist will determine if the treatment should be used alone or with an oral antidepressant. This will be done under medical supervision through the SPRAVATO® REMS program.

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Dr. Omidvari on Spravato

Watch a two-minute segment on how Spravato works, filmed at our Flatiron office.

What We Treat with Spravato

  • A small plant pushing up through a crack in the ground

    Treatment-Resistant Depression (TRD)

  • Sunlight shining through a plant by a window

    Major Depressive Disorder (MDD)

  • Soft plant shadows on a white wall

    Anxiety with Comorbid Depression

What a Session Feels Like

Key Benefits

  • Fully Insurance-CoveredPrior authorization handled by our team.

  • Rapid System ReliefDesigned for fast-acting mental clarity.

  • Non-Surgical & Needle-LessA comfortable, non-invasive experience.

A calm treatment room with a reclining chair, side table, books and a wall clock

The Clinical Setup: Engineered for Safety and Comfort

Our dedicated environment ensures your advanced treatment is safe, peaceful, and restorative.

  • Private Rooms
  • Zero-Gravity Chairs
  • Direct Medical Supervision

All Major Insurances Accepted

We make treatment easy and accessible by providing comprehensive superbills for potential out-of-network insurance reimbursement.

  • BlueCross BlueShield
  • United Healthcare
  • Aetna
  • Cigna
  • EmblemHealth
  • Medicare

Not sure if this is the right fit for you?

Let’s connect for a quick, free phone consultation.

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Important safety information

Spravato (esketamine). Spravato carries an FDA Boxed Warning for sedation; dissociation; potential for abuse and misuse; and suicidal thoughts and behaviors. It is a Schedule III controlled substance available only through a restricted program (Spravato REMS). Patients are monitored for at least 2 hours after each dose and must not drive until the next day after restful sleep. Common side effects include dissociation, dizziness, nausea, sedation, vertigo, anxiety, and increased blood pressure. Spravato is not right for everyone; your psychiatrist will decide if it's appropriate.